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anemia algorithm oncology macrocytosis management workup approach bleeding bruising chronic cll extravascular hemolysis hemolytic hemostasis leukemia lymphocytic lymphoma macrocytic mds
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... lymphoproliferative disorders ... #Causes #differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Corpuscular Volume (MCV ... Normal Blood Smear ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Blood Loss ... • Acute Bleed - ... Reticulocytes, MCV ... Anemia of Chronic Disease ... #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
) - Differential ... Blood Loss, Occult ... HgbE, HgbC, etc. ... #Macrocytosis #elevatedMCV ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... plateletcount), peripheral blood ... changes), high MCV ... Diagnosis #Causes ... #Workup #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
, Acute blood loss ... Myelodysplastic syndrome ... #differential # ... diagnosis #causes ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - APLS • Acute ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Lymphoma Treatment ... #hematology #oncology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... hypertension and/or drug treatment ... including white blood ... #diagnosis #causes ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... lymphoproliferative disorders ... microglobulin Treatment ... ’s lymphoma or acute ... workup #oncology #hematology
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