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management bruising product reactions abnormal acidosis algorithm anemia aptt atlas disseminated elevation extravascular hemolysis hemolytic hemostasis key lactate lactic morphology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... coagulation (DIC ... #Causes #differential ... #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... • Disseminated Intravascular ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Coagulation (DIC ... ABO incompatible blood ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... , Liver diseases ... , Bleeding gastric ... #differential # ... hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... deficiency • Liver ... - APLS • Acute ... #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Disseminated intravascular ... coagulation (DIC ... #diagnosis #differential ... #hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
von Willebrand syndrome ... • Acute DIC ... discern these causes ... disease • Acute ... #Diagnosis #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
removal from the blood ... presentations and disease ... - Compartment syndrome ... #Diagnosis #causes ... #typea #typeb #classification
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... eruptions, diarrhea, liver ... coagulopathy & ↑bleeding ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... eruptions, diarrhea, liver ... coagulopathy & ↑bleeding ... #Transfusions #diagnosis ... #management #hematology
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