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diagnosis oncology hemolytic agglutinin algorithm atlas bloodcell chronic cll cold elevatedmcv erythematosus extravascular gap globulin hemolysis leukemia lupus lymphocytic lymphoma
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... lymphoproliferative disorders ... . sickle cell disease ... #Causes #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Etc. ... Unstable hemoglobin disorders ... RBC #Morphology #differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... Macrocytosis, Target Cells ... #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Workup: • Full ... Immunohistochemical studies (to differentiate ... of disease and ... #hematology #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... changes), high MCV anemia ... #Differential # ... #Workup #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
can indicate disease ... lymphoproliferative disorders ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
(e.g. cirrhosis ... of underlying disease ... Routine tests: Cell ... #workup #Differential ... #Diagnosis #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... younger pts) Differential ... sensitize red blood cells ... the RBCs causing intravascular ... #hematology #diagnosis
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... , eg, cyclic neutropenia ... Megaloblastic anemia-rare ... including white blood cell ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
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