7 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... . lupus, CLL, lymphoma ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Malignant • Lymphoma ... Myeloproliferative disorders ... Systemic Lupus Erythematosus ... Serum Sickness Hemolytic ... #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Unstable hemoglobin disorders ... , Malignant lymphoma ... RBC #Morphology #differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... nodosum • Immune hemolytic ... of cases) Classification ... Lymphoma Workup ... #hematology #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... younger pts) Differential ... the RBCs causing intravascular ... #hemolytic #anemia ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... (e.g. thyroid disease ... cyclophosphamide) • Hodgkin ... #Diagnosis #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... changes (POEMS syndrome ... Connective tissue disorders ... gastric tumors • Hematology ... #diagnosis #hematology