8 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... changes), high MCV ... Diagnosis #Causes ... #Workup #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Thrombocytopenia ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
80-100 fL) • Bleeding ... • Hemolysis ... Renal Disease, Liver ... #Classification ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... deficiency • Liver ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... changes (POEMS syndrome ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... #diagnosis #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
antibodies against proteins ... severe thrombocytopenia ... coagulopathy & ↑bleeding ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
antibodies against proteins ... severe thrombocytopenia ... coagulopathy & ↑bleeding ... #Transfusions #diagnosis ... #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology