ecg qtc syndrome acltear hematology disease differential classification causes hepatology rheumatology diagnosis pain bleeding thrombocytopenia activation oncology

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Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
• Decreased Production
•

Causes of Bleeding ... Diagnosis Algorithm ... Thrombocytopenia ... Rare • Drugs (e.g ... #Causes #Hematology

Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80

Causes of Anemia ... 80-100 fL) • Bleeding ... (e.g. ... #Anemia #MCV #Classification ... #Causes #Hematology

Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
- Prior platelet count, family

Causes of Thrombocytopenia ... Diagnosis and Workup ... - History of bleeding ... #Diagnosis #Causes ... #Workup #hematology

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... #differential # ... diagnosis #hematology

Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
• Epidemiology: young adults 20-30, older 50-70
•

translocation • Types: Classification ... Hepatosplenomegaly, cytopenias(bleeding ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology

Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of

Macrophage Activation ... leukopenia, anemia, and thrombocytopenia ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology

Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear

extramedullary disease ... infiltrates (anemia, thrombocytopenia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis

Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly

by bleeding (petechiae ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

Classification: ... permanent alopecia Differential ... Arthritis: • Joint pain ... Chronic B-cell activation ... #Rheumatology

Blood Transfusion Reactions

Immune Mediated:
• Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.

: Fever, flank pain ... severe thrombocytopenia ... coagulopathy & ↑bleeding ... #Transfusion #diagnosis ... #management #hematology

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