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management oncology activation algorithm bleeding cryofibrinogenemia cryoglobulinemia cryoglobulins eosinophils erythematosus hemostasis hes hypereosinophilia leukemia lupus macrophage mas myelodysplasia myelodysplastic nonpalpable
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Asthma Tugs (vasculitis ... Hypereosinophilic Syndrome ... Diagnosis #Causes ... #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... Secondary Causes ... Hypereosinophilia #Syndrome ... #diagnosis #hematology ... #differential #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... , Vasculitides, ... IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Diagnosis Framework ... ESRD & CAD • Eosinophilic ... cell activation syndrome ... #Diagnosis #hematology ... #allergy
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... Cryoglobulinemia Syndrome ... cryoglobulinemia syndrome ... 20% Sjögren's syndrome ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... differential #diagnosis ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... hypersensitivity syndromes ... Macrophage #Activation #Syndrome ... #Hematology #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... DDX: Rule Out Secondary ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
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