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hemolytic agglutinin atlas bloodcell causes chronic cll cold erythematosus extravascular hepatitis hodgkins injury intravascular liver lupus lymphocytic management microscopy monoclonal
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... . lupus, CLL, lymphoma ... Extravascular #Causes #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Chemotherapy (e.g ... , McLeod blood group ... RBC #Morphology #differential ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... : Acute blood loss ... , Acute hemolysis ... #Diagnosis #Algorithm ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... or acute leukemia ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Acute leukemias ... extramedullary disease ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... younger pts) Differential ... #hemolytic #anemia ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #diagnosis #classification ... #hematology #oncology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... cell lung CA, lymphoma ... intestines, white blood ... #diagnosis #algorithm ... #hepatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... • Acute cutaneous ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... and leukemia •
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