11 results
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... Myelodysplastic syndrome ... myeloid leukemia ... #hematology #secondary
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Diagnosis Algorithm ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... #Diagnosis #Algorithm ... #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Diagnosis Algorithm ... Causes: Chronic ... #Macrocytosis # ... #Diagnosis #Algorithm ... #Causes #Hematology
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Diagnosis Algorithm ... hypereosinophilic syndrome ... Hyper-lgE (Job) syndrome ... ABPA), Gleich syndrome ... #Diagnosis #Algorithm
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Chronic ... • Nephrotic syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... Diagnosis #Algorithm
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Diagnosis Algorithm ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #Pruritus #secondary ... Diagnosis #Algorithm
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology