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diagnosis rheumatology vasculitis acute aki clinical erythematosus gammopathy injury kidney lupus mgus nephrology paraproteinemias significance sle systemic types vasculitides
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... : - Single monoclonal ... tissue disorder (e.g ... diagnosis #types #classification ... #rheumatology #
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
capillary leak syndrome ... • Cryoglobulinemia ... Ig deposition disease ... #Diagnosis #hematology ... #oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
LC deposition disease ... tubulopathy • Monoclonal ... • Hematologic ... #Oncology #Differential ... #Diagnosis #Classification
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... ANCA +MPO) • Cryoglobulinemic ... Low levels mixed cryoglobulinemia ... Serologies for Cryoglobulins ... #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... . hematologic) ... leukemia • Lung cancer ... • Cervical cancer
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