8 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... associated with systemic ... #PT #aPTT #Prolonged ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and the aPTT ... • Reduced liver ... associated with systemic ... amyloidosis #Abnormal ... #PT #aPTT #Prolonged
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Increased Requirement (e.g ... Deficiency - Abnormal ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Chronic Disease Normal ... Chronic Disease (e.g ... #Causes #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... halt nail growth (e.g ... discoloration) • Liver ... #Differential # ... Diagnosis #Algorithm
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm ... Destruction • Abnormal ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... selected cases: INR/PT ... , aPTT(liver disease ... changes), high MCV anemia ... bypass), LFT (liver
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
with leukopenia, anemia ... thrombocytopenia • Liver ... Hypofibrinogenemia • ↑ PT ... ↑ PTT • ↑ Fibrin ... Diagnosis #Management #Hematology