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diagnosis causes dermatology abnormal aptt generalized management prolonged pruritus activation bleeding bruising hemeonc hemophagocytic hlh lymphohistiocytosis macrophage mas naildisorders primary
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Diagnosis Algorithm ... Rare • Drugs (e.g ... Vascular System ... Iatrogenic) • Liver ... #Causes #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
to Systemic Diseases ... discoloration) • Liver ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... • Cholestatic liver ... disease Creatinine ... Pruritus #primary #secondary ... #dermatology #Differential
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... associated with systemic ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... associated with systemic ... Causes #diagnosis #differential ... #hematology #coagulation
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... (eg, systemic juvenile ... thrombocytopenia • Liver ... Hypofibrinogenemia • ↑ PT ... Diagnosis #Management #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... • Cholestatic liver ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... STX11, STXBP2 • Secondary ... ▪ Autoimmune diseases ... - Elevated liver ... Hematopoietic stem
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