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diagnosis causes abnormal aptt coagulation prolonged activation bleeding bruising conjugated direct gastroenterology hyperbilirubinemia macrophage management mas rheumatology syndrome
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Diagnosis Algorithm ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... #Differential # ... gastroenterology #hepatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Diagnosis Algorithm ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Causes #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... associated with systemic ... Causes #diagnosis #differential ... #hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... associated with systemic ... Causes #diagnosis #differential ... #hematology #coagulation
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
thrombocytopenia • Liver ... ↑ AST ↑ ALT ↑ bilirubin ... Hypofibrinogenemia • ↑ PT ... Diagnosis #Management #Hematology ... #Rheumatology
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