4 results
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
Syndrome (KICS) ... together with each of criteria ... , Edema, Cachexia ... #diagnosis #management ... #hhv8
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology: • Cytokine ... myalgias, HoTN, edema ... Diagnosis: >3 symptoms ... APML #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... specific diagnostic criteria ... Kaposi sarcoma, HHV8 ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Common Signs and Symptoms ... • Cytokine storm ... pro-inflammatory cytokines ... Diagnostic Criteria ... of 8 HLH-2004 criteria