887 results
Pathophysiology and Effects of Insulin Deficiency

#Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
Pathophysiology and Effects ... Pathophysiology #Endocrinology
Effects of Parathyroid hormone (PTH) and Calcitonin on Calcium and Phosphate Metabolism

#Parathyroid #hormone #PTH #Calcitonin #phosphate
Effects of Parathyroid ... pathophysiology #endocrinology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus
Calcium - Net Effect Hypercalcemia:
   ↑ intestinal
Hormone (PTH) Effect ... Calcium - Net Effect ... Phosphorus - Net Effect ... pathophysiology #endocrinology
Exogenous Testosterone Side Effects
 • Mood disorder, Depression, Aggression
 • ↑ Erythropoiesis
 • Hypogonadism +/-BPH, prostate
Testosterone Side Effects ... symptoms #steroids #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... definitively cause/effect ... DM2 #diabetes #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
failure Common Side Effects ... definitively cause/effect ... DM2 #diabetes #endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
CKD Common Side Effects ... DM2 #diabetes #endocrinology
Insulin Comparison Chart

Insulin Types - Onset (hours) - Peak Glycemic Effect (hours) - Duration (hours)
 •
Peak Glycemic Effect ... pharmacology #diabetes #endocrinology
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
hypoglycemia risk and effect ... medications #diabetes #endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Significant Adverse Drug Effects ... diagnosis #management #endocrinology