1269 results
Pathophysiology and Effects of Insulin Deficiency

#Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
Pathophysiology and Effects ... #Ketoacidosis #Diabetes ... Pathophysiology #Endocrinology
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
Comparison of anti-diabetic ... manage Type 2 diabetes ... hypoglycemia risk and effect ... #medications #diabetes ... #endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
CKD Common Side Effects ... #Summary #DM2 #diabetes ... #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
failure Common Side Effects ... definitively cause/effect ... #Summary #DM2 #diabetes ... #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... definitively cause/effect ... #Summary #DM2 #diabetes ... #endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... Significant Adverse Drug Effects ... #Euglycemic #Diabetic ... diagnosis #management #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... drugs include side effects ... Side effects include ... Medications #DM2 #Diabetes ... #Endocrinology
Insulin Comparison Chart

Insulin Types - Onset (hours) - Peak Glycemic Effect (hours) - Duration (hours)
 •
Peak Glycemic Effect ... #pharmacology #diabetes ... #endocrinology
Diabetes Morning Hyperglycemia - Dawn Phenomenon vs Somogyi Effect 

When patients FBG's are elevated each morning
Diabetes Morning ... those without diabetes ... patients without diabetes ... #Fasting #Diabetes ... Diagnosis #Management #Endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... to the incretin effect ... Common side effects ... Pharmacology #Dosing #Diabetes ... #DM2 #Endocrinology