318 results
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
Comparison of anti-diabetic ... manage Type 2 diabetes ... hypoglycemia risk and effect ... #pharmacology #pharmacotherapy ... #endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... CKD Common Side Effects ... Sulfonylureas #Pharmacology ... #Summary #DM2 #diabetes ... #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... failure Common Side Effects ... definitively cause/effect ... #Summary #DM2 #diabetes ... #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... definitively cause/effect ... Receptor #Agonists #Pharmacology ... #Summary #DM2 #diabetes ... #endocrinology
Insulin Comparison Chart

Insulin Types - Onset (hours) - Peak Glycemic Effect (hours) - Duration (hours)
 •
Peak Glycemic Effect ... Comparison #Table #pharmacology ... #diabetes #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... drugs include side effects ... Side effects include ... SGLT2 #Inhibitors #Pharmacology ... #Endocrinology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... ) Common Side Effects ... • Euglycemic diabetic ... #Summary #DM2 #diabetes ... #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... disease Common Side Effects ... #Metformin #Pharmacology ... #Summary #DM2 #diabetes ... #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... Common side effects ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology