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differential erythematosus lupus msk pain systemic approach rheumatoid vasculitis autoantibodies chronic classification cll disease hand hematology inflammatory laboratory leukemia lymphocytic
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... mycobacterial), RA ... , SLE, psoriatic ... #rheumatology # ... approach #workup
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... (RA) and many other ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Arthritis of the Hand - Arthritis Patterns Osteoarthritis: • Osteoarthritis of the hand usually involves the DIP and
ulnar deviation • SLE ... PIP + Wrist = RA ... PsA, Sickle cell anemia ... patterns #hand #diagnosis ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... anemia 4% - Myositis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... Symmetrical: • RA ... #Diagnosis #MSK
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
- Signs and Symptoms ... Musculoskeletal: Joint ... Hematological: Anemia ... #RA #Signs #Symptoms ... #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... (RA) is considered ... the presence of anemia ... features suggest RA ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... : • Joint pain ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... #workup #oncology ... #hematology
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