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Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... SinaiBmoreIMRes #Liver ... FunctionTest #LFTs #Elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Phosphatase (ALP) Elevation ... disturbance (obstructed liver ... Highest • Bone • Liver ... Other causes of elevation ... consult ALP elevation
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... Injury • AST/ALT elevation ... or Cholestatic Liver
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... to 10-20-fold elevation ... post-partum • Typical clinical ... to 10-20-fold elevation ... post-partum • Typical clinical
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... Identify Acute Liver ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Causes of Acute Liver ... artery: Shock liver ... Bilirubin - +/- elevation ... Enzyme Elevation
C-REACTIVE PROTEIN Discovered by Tillett & Francis in 1930. First identified as a substance in the serum
synthesized by the liver ... Normal or minor elevation ... mg/L: Moderate elevation ... 10.0 mg/L: Marked elevation ... 50.0 mg/L: Severe elevation
Schema for documenting a type 1 MI, type 2 MI, or non-MI troponin elevation based on
non-MI troponin elevation ... based on clinical ... Infarction #Troponin #Elevation
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
evaluation of the clinical ... /or suspicious clinical ... the remainder, a clinical ... magnitude of enzyme elevation ... and clinical context
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... ALT: • AST: liver ... In liver, 80% of ... primarily within liver ... hepatocyte - Elevation
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