24 results
The algorithm below shows how pre-test probability could be combined with various criteria to determine which
require empiric acyclovir ... The risk of acyclovir-induced ... favor the use of acyclovir ... -Acyclovir is nephrotoxic ... to all encephalopathic
Differential diagnosis for toxic/metabolic encephalopathies - Patterns on Brain Imaging

Cynthia Czawlytko, MD @drcyncity

#Differential #diagnosis #encephalopathies #encephalopathy
toxic/metabolic encephalopathies ... Differential #diagnosis #encephalopathies
Acyclovir - Pharmacology Summary

 • Mechanism of Action: Nucleoside analog - selectively inhibits viral replication of
Acyclovir - Pharmacology ... TheIDtrivia #Acyclovir
Legionnaire's Disease - Extrapulmonary organ involvement: CNS: Mental confusion, encephalopathic, headache. Cardiac: Relative bradycardia. GI: Loose
Mental confusion, encephalopathic
Urine Microscopy - Kidney Stones and Crystals 

Uric Acid, Cystine, Hippurate, Cloth Fiber, Tyrosine, CaOx, CaP,
CaCO3, Struvite, Acyclovir
Varicella (Chickenpox) - Crops of vesicles in various stages of healing 

Treatment 
• Healthy g 12
Immunocompromised or > 12: Acyclovir
Antibiotics and CNS Diffusion

1. Drugs with good CNS diffusion:

- Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole

2. Drugs
β-lactam agents, Aciclovir
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Methotrexate, Orlistat, Acyclovir
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Crystal nephropathy: Acyclovir
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
He remained encephalopathic