13 results
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Diagnosis Algorithm ... oral intake Renal ... Nonreabsorbable anions • Renal ... tubular acidosis • Gitelman's ... #Causes #Classification
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... gastrointestinal K loss • Renal ... • Renal tubular ... Bartter's syndrome, Gitelman's
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Diagnosis Algorithm ... Extra-renal Losses ... loss (Diarrhea) Renal ... Bartter syndrome, Gitelman ... #causes #potassium
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
(renal potassium ... Sjögren syndrome, Renal ... diarrhea Potential Complications ... Rhabdomyolysis Treatment ... nephrology #management #pathophysiology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... life threatening complications ... suggests extra-renal ... causes • Laxative ... Bartter syndrome, Gitelman
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... Villous adenoma Renal ... chewing tobacco, Renal ... diuretic use), Gitelman's
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
HAGMA • Late complication ... HYPOTENSION → renal ... vasoconstriction → decreased renal ... perfusion → renal ... Cast formation: Renal
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
HYPOTENSION -> renal ... vasocontriction-> decreased renal ... renal ischemia ... Cast formation: Renal ... Management #Summary #causes
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... To prevent hypokalemia ... patient has good renal ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Bleeding (64%) • Renal ... Treat primary cause ... #treatment #management ... #hematology