9 results
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... ≥100): SIADH, Renal ... Present (Uosm <100): Renal ... Hypervolemia with poor renal ... #differential #
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... Algorithm Isotonic ... Syndrome, Chronic Renal ... #causes #nephrology ... #sodium #low
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
HYPOTENSION -> renal ... vasocontriction-> decreased renal ... renal ischemia ... Cast formation: Renal ... #Summary #causes
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
Management of Hyponatremia ... SIADH — look for cause ... considerations: Addison's, Renal ... #Management #algorithm ... #treatment #sodium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
HYPOTENSION → renal ... vasoconstriction → decreased renal ... perfusion → renal ... Cast formation: Renal ... #causes #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... Anaphylaxis, Acute Renal ... APML #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Bleeding (64%) • Renal ... Treat primary cause ... #treatment #management ... #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Immunosuppressive agents, Renal ... Etiology: • Pathophysiology ... Reversible course Differential ... • Treatment of ... Syndrome #diagnosis #management
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
• Hypokalemia (renal ... ratio 0.5%) Differential ... Sjögren syndrome, Renal ... Rhabdomyolysis Treatment ... #pathophysiology