13 results
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
Diagnosis Algorithm ... papilledema • Horner syndrome ... ) • Systemic symptoms ... , fever, myalgia ... arteritis • Acute
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... - ACS, AKI, acute ... WBC >100k, + lab signs ... diagnosis #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... : • Common: fever ... Diagnosis: >3 symptoms ... initiation • Differential ... Differentiation #Syndrome
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... and symptoms can ... presents as an acute ... management #treatment #hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... suspicious clinical symptoms ... /signs should be ... presence of metabolic syndrome ... #Enzymes #Differential
Rare Causes of Abdominal Pain
 • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
Mediterranean Fever ... by serositis • Acute ... - May involve symptoms ... Positive Carnett's sign ... Abdominal #Pain #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... noninflammatory Signs ... constitutional symptoms ... - Autoimmune Rheumatologic ... #Joint #pain #Differential
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Cord Disorders - Differential ... and signs below ... Pain reported at level ... MCTD, Sjogren syndrome ... #algorithm
Signs and Symptoms Associated With Different Headache Etiologies
 • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... vasoconstriction syndrome ... #headache #signs ... #symptoms #clues ... #differential #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Pleural effusions • Acute ... Induced Lupus: • Symptoms