17 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... ongoing ↑ LFTs or symptoms ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Hepatomegaly - Differential ... Diagnosis Algorithm ... • Budd-Chiari Syndrome ... Hepatitis • Drug Induced ... #Causes #Hepatology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
to Headaches - Differential ... Diagnosis Algorithm ... papilledema • Horner syndrome ... ) • Systemic symptoms ... , fever, myalgia
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... suspected HH based on symptoms ... elevated iron indices ... #diagnosis #management ... #hepatology #gastroenterology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... /signs should be ... presence of metabolic syndrome ... #Hepatology #Liver ... #Enzymes #Differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... : • Triad of symptoms ... urine • Other symptoms ... #Diagnosis #Management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Actively maintained fever ... (→ 3-1) Drug induced ... hyperthermia crisis (late sign ... #Hyperthermia #Differential ... Checklist #Diagnosis #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... endothelial damage • Induce ... Diagnosis: >3 symptoms ... initiation • Differential ... APML #diagnosis #management
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
failure PBC Signs ... and Symptoms: ... bile ducts Differential ... Sarcoidosis, Drug-induced ... diagnosis #workup #hepatology