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diagnosis disease hematology primary treatment addisons adrenal biliary biphasic chagas checklist cholangitis cirrhosis crisis criticalcare disorders endocrinology hemophagocytic hepatology hlh
Common organ involvements and symptoms in Sarcoidosis Lung 89-99% - Cough, dyspnoea, wheezing and stridor Skin 16-32% -
Common organ involvements ... Sarcoidosis Lung ... and syncope #Sarcoidosis ... #organ #involvements ... #signs #symptoms
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
Sarcoidosis Non-caseating ... pts (extensive organ ... Constitutional: Fever ... #Diagnosis #Symptoms ... #Signs #Pulmonary
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
higher incidence in lung ... >heart>liver>kidney ... Conditioning regimen Signs ... EBV viral load, signs ... oncology #diagnosis #management
Sarcoidosis Stage 1 - Bilateral LAD without involvement of lung parenchyma Stage 2 - Bilateral LAD with involvement
Sarcoidosis Stage ... gland sweling, fever ... @AnnKumfer #Sarcoidosis ... Stages #Staging #Signs ... #Symptoms #Summary
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... granulomas within the lungs ... and damage of organs ... #Diagnosis #Management ... #Signs #Symptoms
Biphasic Illness of Leptospirosis Some patients do not progress to severe disease. Others, rapidly develop severe disease
brief interval symptom ... -14 days): • Fever ... suffusion (redness w/o exudate ... Shock and multi-organ ... Diagnosis #Illness #Signs
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Adrenals: • Lung ... vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... endocrinology #diagnosis #signs
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
failure PBC Signs ... and Symptoms: ... or higher • Liver ... Lymphoma and solid organ ... viral infections, Sarcoidosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... and symptoms can ... with multiple organ ... following: • Fever ... Lymphohistiocytosis #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... WBC >100k, + lab signs ... of end organ damage ... TLS #diagnosis #management
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