24 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Sarcoidosis Non-caseating ... Clinical: • Disease ... Constitutional: Fever ... #Diagnosis #Symptoms ... #Signs #Pulmonary
Sarcoidosis
Stage 1 - Bilateral LAD without involvement of lung parenchyma
Stage 2 - Bilateral LAD with involvement
Sarcoidosis Stage ... disease with infiltrates ... gland sweling, fever ... Stages #Staging #Signs ... #Symptoms #Summary
Common organ involvements and symptoms in Sarcoidosis
Lung 89-99% - Cough, dyspnoea, wheezing and stridor
Skin 16-32% -
in Sarcoidosis ... Lung 89-99% - Cough ... and syncope #Sarcoidosis ... #diagnosis #signs ... #symptoms
Bilateral B-Lines in case of Pneumonia on Lung POCUS

Young healthy pt with fever/dyspnea. POCUS lung exam
POCUS lung exam ... disease, interstitial ... Lung POCUS shows ... partially seen shred sign ... Lung POCUS invaluable
Biphasic Illness of Leptospirosis
Some patients do not progress to severe disease. Others, rapidly develop severe disease
develop severe disease ... brief interval symptom ... -14 days): • Fever ... suffusion (redness w/o exudate ... Diagnosis #Illness #Signs
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Adrenals: • Lung ... vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... endocrinology #diagnosis #signs
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... granulomas within the lungs ... patients have no symptoms ... #Diagnosis #Management ... #Signs #Symptoms
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... Less Specific Signs ... Chest x-ray: signs ... acute HF → no signs ... coronary artery disease
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
failure PBC Signs ... and Symptoms: ... but elevated as disease ... viral infections, Sarcoidosis ... , IgG4 related disease
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
higher incidence in lung ... >heart>liver>kidney ... Conditioning regimen Signs ... EBV viral load, signs ... oncology #diagnosis #management