13 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... • Pulmonary: pleural ... Disease #diagnosis #management ... #treatment #rheumatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
also observed in adults ... Diagnosis: HLH signs ... and symptoms can ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... the chest/trunk Symptoms ... Treatment - Mild ... AOSD #diagnosis #rheumatology ... #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... rash) • Heart, lung ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rheumatoid arthritis, adult-onset ... : • Pleural effusions ... Serositis: • Pleural ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... systemic sx + signs ... Treatment of GCA ... them, but urgent rheumatology ... #Management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
and masses, and exudative ... pleural effusions ... gradually with symptoms ... Fever 4. ... Pulmonary #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Epidemiology: • Young adults ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #