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diagnosis differential erythematosus lupus sle systemic signs autoantibodies autoimmune joint management mimickers monoarthritis monoarticular myopathy oligoarthritis oligoarticular pain polyarthritis polyarticular
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... anemia 4% - Myositis ... 4% - Lung involvement ... autoantibodies #signs ... #symptoms #mimickers
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
peripheral vs axial (spine ... noninflammatory Signs ... constitutional symptoms ... Differential #Diagnosis #MSK ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... : • Pleural effusions ... Serositis: • Pleural ... • Transverse Myelitis ... Induced Lupus: • Symptoms
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... forward of the spine ... • Nonerosive arthritis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Xerotrachea • NSIP: Pleural ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
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