8 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... APML #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... life-threatening Differential ... Imaging - CT Chest ... stimulation - Single fiber ... Gravis #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Framework and Management ... ) • AKI: BUN/Cr ... fluid/Lactated ringers ... #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
by 24 hours or longer ... circulation: MCA ACA ... Reversible course Differential ... epilepticus Treatment ... #diagnosis #management
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
Intraoperative ... remember to tailor treatment ... reservoir bag and APL ... Checklist #Diagnosis #Management ... #Workup #Cardiology
STEMI Equivalents on ECG
 • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
J point • De Winter ... syndrome - J-point ... of the leads l, aVL ... EKG #diagnosis #differential ... #cardiology #electrocardiogram
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
suspected) - CT chest ... interventional radiology ... - Occurs after CAR-T ... : - Seen with AML ... (~20 %) and APL
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Serum Copper • Chest ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... hematology #oncology #management