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diagnosis syndrome disease sle arteritis druginduced erythematosus gca giantcell systemic 2ndline activation approach behcets cerebritis classification cns comparison cppd deposition
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... thiazidic, PPI, ACE, calcium-b ... • Immunologic Workup ... • Immunologic Workup ... comparison #table #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Secondary prevention (statin ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... thiazidic, PPI, ACE, calcium-b ... • Immunologic Workup ... #DIL #rheumatology ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... • Treatment: ... TLS #diagnosis #management ... #hematology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... refractory disease Arthritis ... #management #pharmacology ... #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... - Gram stain and ... crystals (gout) or calcium ... joint • Systemic lupus ... diagnosis #testing #Rheumatology
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
Treatment of giant ... cell arteritis ... MTX or TCZ in case ... #Management #Relapses ... #Indications #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Lyme), reactive arthritis ... Like in this case ... Joint #Pain #MSK #rheumatology ... #approach #workup
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