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diagnosis differential hematology macrocytic gastroenterology macrocytosis aafp b12 celiac cobalamin elevatedmcv falls folate folicacid gastrointestinal geriatrics hemolytic homocysteine hospitalization iron
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Anemia • 812 ... , Folate Deficiency ... Hypothyroid • Liver Disease ... #diagnosis #algorithm ... #hematology #workup
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... evaluation of macrocytic ... the most likely cause ... recovery also causes ... #Workup #AAFP
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... of Iron Deficiency ... Test for celiac disease ... if serology is positive ... #Evaluation #workup
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Differential Diagnosis Algorithm ... DAT (-) → G6PD Deficiency ... Hypochromic & microcytic ... malignancy, autoimmune disease ... #causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Differential Diagnosis Algorithm ... • Dietary Deficiency ... #Macrocytic ... #Causes #Hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... • Common Causes ... : • Worsening macrocytic ... to IBD, celiac disease ... total body stores Evaluation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... or folic acid deficiency ... treatments • Copper deficiency ... Workup: • Complete
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
the recumbent position ... the horizontal position ... phlebotomy/ blood work ... during clinical evaluations ... of renal disease
Celiac Disease - Diagnosis Algorithm IgA TTG has high sensitivity and specificity of ~ 98% and is
Celiac Disease - ... serologic marker for evaluating ... IgA deficiency affects ... -A positive test ... gastroenterology #workup
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
Evaluation of Recurrent ... embolism - Severe anemia ... diabetic, B12 deficiency ... Numbness in feet, positive ... #Differential #Evaluation
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