18 results
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
- Differential Diagnosis ... Algorithm Tumours ... Disease - Skull/spine ... Ricketts - Diffuse Pain ... #Causes
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... unilateral flank pain ... Nephrology if cause ... identified by UW IM ... #Algorithm #Workup
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... compression by fractured ... Cord Causes: 1 ... myelopathy - Vit B12 ... differential #algorithm
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
Causes of spinal ... HIV) - Vitamin B12 ... , Copper deficiency ... Vertebral burst fracture ... #differential #diagnosis
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework ... • Fracture • Arthritis ... Neuropathy (DM, Vit B12 ... , B6, Cu deficiency ... etc) • Spinal
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
long - Delay>12 ... Syndrome • Syndrome caused ... injury or after IM ... • Diagnosis: ... - Intense pain
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • recurrent fractures ... Pernicious anemia/B12 ... mineralization Symptoms ... - Frequent fractures
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... GI - glossitis (pain ... , can consider IM ... #diagnosis #management
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Fatigue and IBD Algorithm ... restricted diet/deficiency ... symptoms even if ... /other causes • ... #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
or without back pain ... Bilateral signs and/or symptoms ... Check Vitamin B12 ... • Nutritional Deficiency ... #management #neurology