12 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Intestine - Other causes ... - Bone symptoms ... - Pain -> RUQ
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Pathologic / Fragility Fractures ... - Differential Diagnosis ... Algorithm Tumours ... Ricketts - Diffuse Pain ... #Causes
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • recurrent fractures ... Malnutrition • Wilson's disease ... mineralization Symptoms ... : • Other causes
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
2) Presence of symptoms ... , liver, renal disease ... #EM #IM #Nephro ... #Differential #Algorithm ... #Ddxof
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... unilateral flank pain ... nephrolithiasis • Symptoms ... identified by UW IM ... #Algorithm #Workup
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... Signs and Symptoms ... : • Alkaline phosphatase ... Diagnosis: • ... #workup #hepatology
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Whipple Disease ... Management Caused ... Tropheryma whipplei Symptoms ... Abdominal pain; ... #diagnosis #algorithm
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Diagnosis Framework ... did not yield a diagnosis ... changes • Urinary symptoms ... dysfunction • PSC ... hernia • Rib fracture
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
arrived w/severe abd pain ... Similar symptoms ... Assc symptoms include ... or PenG 800K U IM ... Infectious Diseases
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Hypercortisolism - Diagnosis ... , oral cavity) Caused ... , pathological fractures ... e.g., glucose-6-phosphatase ... #signs #symptoms