35 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Pathogenesis and clinical ... Incr Skeletal fractures ... • Short stature ... sleep apnea, cor pulmonale
Pulmonary Embolism - Risk Stratification and Prognostication based on scores and clinical features

 • Bova score
Pulmonary Embolism ... Prognostication based on scores ... and clinical features ... @nickmmark #Pulmonary ... prognostication #diagnosis #management
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS) - Differential ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology
Haglund Syndrome - MSK Radiology
Imaging Findings:
 • The Haglund Deformity (enlarged superior margin calcaneal posterior process)
- MSK Radiology ... Differential diagnosis ... • Stress fracture ... #Heel #clinical ... #mri #clinical
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... : Starts in legs ... #diagnosis #management
Freiberg Infraction - MSK Radiology
Imaging Findings:
 • Sclerosis of the 2nd MT head with flattening of
Freiberg Infraction - MSK ... Controversy: Subchondral fracture ... factors include: Short ... Differential diagnosis ... #mri #clinical
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... renal failure Clinical ... Features: • Many ... Pulmonary: dyspnea ... anterior/posterior MSK
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... Framework and Clinical ... HF • Moderate pulmonary ... : - Impaired short-term ... Manifestations #Differential
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Features: • Synovitis ... Diagnosis: • A clinical ... #Rheumatology # ... diagnosis #management