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Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... (ALT or AST > ALP ... Wilsons, Pregnancy - AFLP ... Cholestatic Pattern (ALP
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... for the liver ALP ... Transaminase, ALP ... / ULN ALT) / (ALP ... / ULN ALP)
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... in 1923 Low ALP ... 1948 by Rathbun ALP ... severe mobility/functional ... is critical for
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
• AST/ALT > ALP ... GGT/5-NT: ↑ - ALP ... disease - If ALP ... Tests of synthetic function ... hemolysis) • ALP
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
of Pregnancy (AFLP ... TTPHUS #HELLP #AFLP
Causes of AKI in Pregnancy - Differential Diagnosis Creatinine - Platelets - Transaminases - LDH - PT/PTT
Nephritis • AFLP
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... post-partum • Typical clinical ... of Pregnancy (AFLP ... post-partum • Typical clinical ... diagnosis #icp #HELLP #AFLP
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
(Alk phos/ULN ALP ... • AST/ALT > ALP ... Cholestasis • ALP ... disease • If ALP ... • Elevation of ALP
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Maternal Support - Critical ... iMedEducation #AFLP
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... Diagnosis Algorithm ALP ... - Increased ALP ... Surgical consult ALP ... #Phosphatase #ALP
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