10 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Decreased ENaC channel function ... Aldosterone Release: ACE inhibitors ... Aldosterone Receptor Function ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... heparin (UFH): Inhibits ... the function of ... heparin (LMWH): Functions ... #Pharmacology #Pathophysiology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... Stimulates Insulin, Inhibits ... has very minimal chance ... check the kidney function ... Renal #Dosing #Pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... inducers (↑) and inhibitors ... by inducers or inhibitors ... #Chemotherapy #Oncology ... Interactions #Table #Pharmacology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Summary Lung Abscess ... Etiology: • Necrosis ... Pathophysiology ... foreign body, cancer
Checkpoint inhibitors and indications
Anti CTLA-4 antibody:
 • Ipilimumab: Malignant melanoma, Renal cell cancer
Anti-PD-1 antibody:
 • Nivolumab:
Checkpoint inhibitors ... , Gastric cancer ... #Checkpoint #inhibitors ... #indications #oncology ... #pharmacology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
outflow - PDE-5 inhibitors ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology ... #Urology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... necrosis factor-α inhibitors ... Lymphoma • Lung cancer ... emboli • Lung abscess ... Treatment With TNF Inhibitor
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... necrosis factor-α inhibitors ... Lymphoma • Lung cancer ... emboli • Lung abscess ... Treatment With TNF Inhibitor
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
ventricular ejection fraction ... Strategies: • Assess ... Strategies: • Assess ... Cardiotoxicity #cardiology #oncology ... #pharmacology #