13 results
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
body mass index; VTE ... #DOAC #VTE #Malignancy ... #Cancer #Algorithm ... Anticoagulation #Management ... #Hematology #Oncology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
algorithm for VTE ... thrombosis in cancer ... #Cancer #Algorithm ... Anticoagulation #Management ... #Hematology #Oncology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
decreased glycosylated fraction ... hemopathies, solid cancers ... Disease #diagnosis #management ... #treatment #rheumatology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... APML #diagnosis #management ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... B-LNH), solid cancers ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline

First Line Treatment for HCC with Preserved
Preserved Liver Function ... Systemic #Treatment #Management ... #Hepatology #Gastroenterology ... #oncology #Pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
specific loss-of-function ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Clotmaster Consensus 2019: Duration of Therapy for Venous Thromboembolic Disease
 • Superficial Venous Thrombosis
 • Upper
Thrombophilia • Cancer ... DeLoughery @Bloodman #VTE ... anticoagulation #duration #management ... #DVT #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
thrombocytopenia, or functional ... lymphoid organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis