9 results
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... with good renal function ... Anticoagulation #Pharmacology ... #Table
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... #Chemotherapy #Oncology ... #Interactions #Table ... #Pharmacology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... : Inhibits the function ... heparin (LMWH): Functions ... #Pharmacology #Pathophysiology ... Heparins #LMWH #UFH #DOAC
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... available lab test to assess ... per treatment table ... ✔ Assess patient-specific ... Management #Treatment #pharmacology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
thrombosis in cancer ... §Assess drug-drug ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Management #Hematology #Oncology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Etiology: • Necrosis ... Pathophysiology ... antibiotics once stable ... shows a small, stable ... foreign body, cancer
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Nephron and their Functions ... Nephron #Segments #Function ... #Pathophysiology ... #Tubules #Table ... #Pharmacology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Etiology • Actual ... etiology remains ... Avoid Warfarin and DOAC ... during Delivery • Stable ... studies show no ↓ LV function
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
ventricular ejection fraction ... Strategies: • Assess ... Strategies: • Assess ... Cardiotoxicity #cardiology #oncology ... #pharmacology #