10 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... inducers #inhibitors #Chemotherapy ... #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... with good renal function ... Anticoagulation #Pharmacology ... #Table
Major Chemotherapy Toxicities - AntiNEOPlastic Man Mnemonic

Common Toxicities with Traditional Chemotherapeutic Medications 

Originally posted on pharmacologyweekly
Major Chemotherapy ... longer active) #Chemotherapy ... SideEffects #Adverse #Pharmacology ... AntiNeoplastic #Man #Oncology ... #Table
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... : Inhibits the function ... heparin (LMWH): Functions ... #Pharmacology #Pathophysiology ... Heparins #LMWH #UFH #DOAC
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Nephron and their Functions ... Nephron #Segments #Function ... #Pathophysiology ... #Tubules #Table ... #Pharmacology
Testicular Cancer - Treatment Related Toxicities

Bleomycin, Cisplatin, Etoposide, lfosfamide
Tinnitus & Hearing Loss
Neurotoxicity
Pulmonary Fibrosis
Hypotension
Nephrotoxicity
Skin Hyperpigmentation
Hemorrhagic Cystitis
Myelosuppression
Peripheral Neuropathy

Ashley
Testicular Cancer ... #Testicular #Cancer ... #chemotherapy # ... toxicology #Toxicities #pharmacology ... #oncology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Etiology • Actual ... etiology remains ... Avoid Warfarin and DOAC ... during Delivery • Stable ... studies show no ↓ LV function
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Etiology ... Lung Abscess Pathophysiology ... antibiotics once stable ... shows a small, stable ... foreign body, cancer
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Autoimmune disease, Cancer ... chemotherapy, Immunosuppressive ... Hypercalcemia Etiology ... : • Pathophysiology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
ventricular ejection fraction ... Cardiotoxicity #cardiology #oncology ... #pharmacology # ... toxicity #chemotherapy