7 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... inducers (↑) and inhibitors ... #Chemotherapy # ... Oncology #Hematology ... Interactions #Table #Pharmacology
Dyspnea - Considerations with Malignancy
Directly Malignancy Related:
 - Lymphangitic spread to lung
 - Malignant pleural effusion
Treatment Related: - Chemotherapy ... NEJMcps1414168 #dyspnea #algorithm ... differential #diagnosis #oncology ... #cancer #malignancy
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Differential Diagnosis Algorithm ... in Cancer UOsm ... deficiency (CTLA4 inhibitors ... #algorithm #nephrology ... #oncology
Testicular Cancer - Treatment Related Toxicities

Bleomycin, Cisplatin, Etoposide, lfosfamide
Tinnitus & Hearing Loss
Neurotoxicity
Pulmonary Fibrosis
Hypotension
Nephrotoxicity
Skin Hyperpigmentation
Hemorrhagic Cystitis
Myelosuppression
Peripheral Neuropathy

Ashley
Testicular Cancer ... #Testicular #Cancer ... #chemotherapy # ... toxicology #Toxicities #pharmacology ... #oncology
Causes of Urinary Tract Obstruction - Differential Diagnosis Algorithm
Upper Tract - Bladder NOT distended on ultrasound,
Differential Diagnosis Algorithm ... NOT distended on ultrasound ... Fibrosis • Cancer ... Ureteropelvic junction ... #Causes #Urology
Checkpoint inhibitors and indications
Anti CTLA-4 antibody:
 • Ipilimumab: Malignant melanoma, Renal cell cancer
Anti-PD-1 antibody:
 • Nivolumab:
Checkpoint inhibitors ... , Gastric cancer ... #Checkpoint #inhibitors ... #indications #oncology ... #pharmacology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
ventricular ejection fraction ... system (RAAS) inhibitor ... Cardiotoxicity #cardiology #oncology ... #pharmacology # ... toxicity #chemotherapy