589 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Maintenance: 10 g ... intervals in 5-g ... QoD to 15 g QD ... of aspiration #Potassium
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
) MECHANISM: Potassium ... DOSING: 8.4 g ... Increase by 8.4 g ... week, up to 25.2 g ... patiromer) is a potassium
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... ratio < 15 mEq/g ... ratio > 15 mEq/g ... #differential #potassium
Checklist Approach to Hypokalemia

Consider risk factors for arrhythmia:
 - EKG changes (especially QT prolongation)
 - Digoxin
incongruous with clinical ... safely, whereas potassium ... Enteral potassium ... Intravenous potassium ... Internet Book of Critical
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
protein ≤ 2.5 g/ ... protein ≥ 2.5 g/ ... albumin #gradient #hepatology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
pernicious anemia) • G-CSF ... nephrology #low #potassium
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... K+ <13 mEq K+/g ... K+ >13 mEq K+/g ... hypokalemia #urine #potassium
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
injury (≥ 1B) - 1 g/ ... days then 20-40 g/ ... Cirrhosis #treatment #hepatology
Tinea Versicolor (Pityriasis versicolor) 
NOT a dermatophyte infection 
Caused by saprophytic, lipid-dependent yeasts 
Clinical 
 •
lipid-dependent yeasts Clinical ... Diagnosis • Potassium ... Tinea #Versicolor #Dermatology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome • Clinically ... suspect underlying hematologic ... Syndrome #HES #Hematology