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hemophagocytic hlh lymphohistiocytosis algorithm antibiotics febrile hemeonc pediatrics rheumatology stepbystep stratification adultonset chronic classification cll fungal hodgkins infections infectiousdiseases leukemia
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... #Algorithm #LP
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... #EBM #Management ... #Pediatrics #Peds ... StepByStep #Algorithm #LP ... Stratification #Fever
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Coxsackie, CMV, EBV ... Prunelle Getten ... #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... age, however the disease ... following: • Fever ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... #management #treatment
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
) B symptoms → fevers ... chemotherapy for low-risk ... disease • Indications ... #hematology #hemeonc ... #diagnosis #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
respiratory symptoms • Fever ... MUCORMYCOSIS • Risk ... Encapsulated yeast • At risk ... : • β-D-glucan ... #Management #Infections
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Risk ... • Dyspnea • Fever ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Onset: Usually in infancy ... Infections (e.g., EBV ... ▪ Autoimmune diseases ... #Management #Hematology
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