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hematology oncology algorithm classification hodgkins lymphoma management pathophysiology agglutinin bandemia blastomycosis causes cbc cell cold comparison disease disorders gravis hemolysis
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... DIC, HELLP - Grafts ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... Lines - Horizontal Grooves ... Systemic #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... - usually at a single ... B-Cell ~90% • Low Grade ... range • High Grade ... #differential #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
originate from a low-grade ... Viral Infection Clinical ... anemia • Cold ... younger pts) Differential ... #hematology #diagnosis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... life-threatening Differential ... myasthenia Diagnosis ... stimulation - Single ... #diagnosis #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Neutrophil (Normal) Differential ... likelihood of negative clinical ... #differential # ... #WBC #CBC #hematology
Ulcerative Blastomycosis Skin Lesion 57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Denies any travel ... Diagnosis? ... heaped up borders); differential ... Blastomycosis #SkinRash #dermatology ... #clinical #photo
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... extranodal) - Tumor grade ... Diagnosis of B-Symptoms ... #differential # ... hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... syndromes with single-lineage ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
General Approach to Anemia - Differential Diagnosis Framework 1) Check reticulocyte count to determine if hypo/hyper-proliferative 2) Exclude
General Approach to Anemia ... - Differential ... Diagnosis Framework ... ) 3) Use MCV & clinical ... diagnosis #hematology
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