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hematology oncology classification comparison hodgkins lymphoma management pathophysiology agglutinin algorithm anemia bandemia blastomycosis cbc cold defects dermatologic disease disorders gpa
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... - usually at a single ... ~90% • Low Grade ... range • High Grade ... #differential #
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... extranodal) - Tumor grade ... Diagnosis of B-Symptoms ... #differential # ... hematology
Ulcerative Blastomycosis Skin Lesion 57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Denies any travel ... Diagnosis? ... heaped up borders); differential ... Blastomycosis #SkinRash #dermatology ... #clinical #photo
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... DIC, HELLP - Grafts ... Defects: Sickle cell ... #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
originate from a low-grade ... Viral Infection Clinical ... malignancies - B-cell ... younger pts) Differential ... sensitize red blood cells
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... life-threatening Differential ... myasthenia Diagnosis ... stimulation - Single ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... syndromes with single-lineage ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
platelet count, Single ... structure and cell ... platelets on smear, as well ... comparison #table #differential ... #diagnosis #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... reticularis Differential ... Diagnosis: Vasculitis ... syndrome • Giant cell ... #rash #diagnosis
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Left Shift: • Cell ... precursors" • Stab cell ... #Bandemia #differential ... #WBC #CBC #hematology
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