114 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... inflammation onto hair ... Destruction of hair ... pathophysiology #diagnosis #signs
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Framework for Hair ... Localized / Focal Hair ... - Broken Hair ... Diffuse Hair ... Examination: • Signs
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Hair Loss (Alopecia ... scalp and facial hair ... (all body hair) ... • Congenital hair ... abnormalities - Hair
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... Erythematosus #SLE ... Manifestations #Signs
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... Photosensitivity, Alopecia ... are evocative of SLE ... management of SLE ... Lupusreference #SLE
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... brittle unmanageable hair ... , Deafness Signs ... complexion, Dry thin hair ... Hypothyroid #Features #Signs
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
• Transient alopecia ... Toxicology #Symptoms #Signs
Primary Dermatologic Nail Disorders - Differential Diagnosis Algorithm
Nail Plate - Pitting
 • Psoriasis
 • Alopecia Areata
Nail
Psoriasis • Alopecia ... Telangiectasia • SLE
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Auto-immune attack on hair ... follicles -> Alopecia ... pathophysiology #signs
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 - Infectious
Focal / Localized Hair ... Loss (Alopecia) ... Reversible - Broken Hair ... • Congenital hair ... abnormalities - Hair