16 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... decreased PLT count: CBC ... K), H. pylori test ... (CVID, WAS), (neurologic ... #Workup #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Meningitis, Myelopathy, Encephalopathy ... Cerebrovascular Disease ... , PRES Pathophysiology ... #rheumatology #
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... to right with bands ... • Autoimmune diseases ... #WBC #CBC #hematology ... #pathophysiology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
Hepatic Encephalopathy ... - Diagnosis and ... other causes of neurologic ... over course of disease ... #Grading #Classification
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Neurocognitive Disorder (HAND ... Diagnosis: MRI ... reversible • HAND ... HIV patients #HAND ... #Neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... skin injury) • Neurologic ... ) Differential Diagnosis ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Posterior Reversible Encephalopathy ... may precede the neurologic ... Shock, Autoimmune disease ... Etiology: • Pathophysiology ... Reversible course Differential
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... Paresthesias: Hands ... - NORMAL CSF WBC ... #neurology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Blood smear - RBC ... younger pts) Differential ... test #cold # ... hemolytic #anemia #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential ... should be based on clinical ... Antimicrobial treatment ... Demyelinating disease ... #diagnosis #AIDS