181 results
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
hyperCalcemia 28% (bone ... 78% (bone marrow ... macrocytic • Bone ... Diagnosis - Clonal bone ... clonal cell in bone
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic Algorithm ... hyperplasia of bone ... breakdown • Anaemia ... Hemolysis #Hemolytic #Anemia ... #Algorithm #Differential
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... Diagnostic Algorithm ... Iron deficiency anemia ... deficiency - Probable bone ... Underproduction #Algorithm
Paget's Disease of Bone

 • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease of Bone ... by an ↑ rate of bone ... and formation of bone ... Pagets #Disease #Bone ... #diagnosis #management
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis Algorithm ... Flow cytometry, Bone ... Alcoholism Bone ... Acquired Aplastic Anemia ... • Congenital bone
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... Low in bone marrow ... suggests appropriate bone ... Algorithm by Dr.
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... and Bone Marrow ... Pancytopenia Fanconi Anemia ... Acquired Aplastic Anemia ... Failure #Aplastic #anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
particular degree of anemia ... Hypoproliferative (i.e. bone ... Index < 2: • Anemia ... Hypogonadism • Bone ... Hyperproliferative (i.e. bone
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Differential Diagnosis Algorithm ... production: • Bone ... suppression • Bone ... marrow failure • Bone ... Differential #Diagnosis #Algorithm
Pancytopenia - Differential Algorithm / Schema

- Bone Marrow Failure
- Bone Marrow Infiltration
- Sequestration / Destruction

#Pancytopenia #Differential
- Differential Algorithm ... / Schema - Bone ... Marrow Failure - Bone ... #Differential #Algorithm