2458 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Virus (EBV, CMV, HHV8 ... Still disease, Infection ... Unknown cause Treatment ... diagnosis #management #treatment
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... activity against HHV ... recommended for KS treatment ... IDSA #Prevention #Treatment ... opportunistic #infections
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
six months of treatment ... Kaposi sarcoma, HHV8 ... Poor adherence to treatment ... Treatment: ... by delaying ART treatment
IDSA Aspergillosis Treatment
 • Invasive pulmonary aspergillosis (IPA)
 • CNS aspergillosis
 • Cardiac Aspergillus infection
 •
Aspergillosis Treatment ... Cardiac Aspergillus infection ... • Aspergillus infections ... of eye Infectious ... Aspergillosis #Treatment
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
IDFellowCase #ID #Infectious ... Diseases #Infections ... Diagnosis #KSHV #HHV
Summary of Infections in which Steroids play a role in treatment
 • TB meningitis
 • TB
Summary of Infections ... play a role in treatment ... (IRIS) (not an infection ... #Indications #infections ... #management #treatment
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... 20%) congenital infection ... herpes virus 6 HHV ... herpes virus 7 HHV ... herpesvirus 8 HHV
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Diagnosis: • Non-Infectious ... take 48 hrs for infections ... Immunocompromise Treatment ... • Secondary to Treatment ... rxn), Secondary infection
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
• unicentric, HHV8 ... Plasmablastic subtype is HHV8 ... myeloma, POEMS) HHV8
Antibiotics for Intraabdominal Infection. 
Use your local antimicrobial susceptibility data for selecting the best empiric treatment!
Intraabdominal Infection ... the best empiric treatment ... intra-abdominal infections ... #pharmacology #treatment