15 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Diagnosis for Pulmonary ... Renal Syndromes ... #Renal #Syndrome ... #differential #
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... - Differential ... Diagnosis Framework ... Kumfer @AnnKumfer #Pulmonary ... #Renal #Syndromes
Miliary Pattern - Chest Radiology
 • Miliary opacities are scattered, small (1 -4 mm) nodules
 •
hematogenous spread of a disease ... Endemic fungi: Histo ... thyroid, melanoma, renal ... #diagnosis #pulmonary ... #CXR #clinical
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... and renal abnormalities ... to exclude are infections ... differential #diagnosis ... #rheumatology #
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... confirm DAH, r/o infection ... • IF staining patterns ... #Renal #Syndromes
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
- HIV infection ... and obstructive pattern ... mediastinitis, chronic renal ... Classification #Diagnosis ... #Differential #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
microscopy and serial ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... #rheumatology # ... diagnosis #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... and renal abnormalities ... Vasculitis Differential ... #Differential #Diagnosis ... #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... Spondyloarthropathies, SLE • Pulmonary ... , Vasculitis (e.g ... #joint #pain #differential ... #diagnosis #rheumatology
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
arthralgias, CV, renal ... Hypereosinophilic Syndrome ... , CNS, skin • Infectious ... #pulmonary #differential ... #diagnosis #comparison