10 results
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
mutation) that alter ... yrs old; F>M Signs ... neurological findings #GiantCell ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
(Composed of T-helper ... & inflammatory cells ... dysrhythmias • Ophthalmologic ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
PO4 and Mg into cells ... Constipation - MSK ... Refeeding #Syndrome #diagnosis ... #pathophysiology ... #symptoms #signs
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees)

 • Incr Axial rotation of thoracic
joints to the pelvis ... -> The pelvis is ... #Scoliosis #pathophysiology ... #msk #diagnosis ... #signs #symptoms
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older ... systemic sx + signs ... required +/- prompt ophthalmology ... #GiantCell #arteritis ... GCA #Temporal #Signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
polymorphisms alter ... various inflammatory cells ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Retina • Ganglion cells ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... • Bilateral signs ... Pleocytosis > 100 cells ... Infections: - Herpes zoster
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... anterior/posterior MSK ... #Management #Signs